
Dott. Giannantonio Spena
 Director of Neurosurgery Unit
 
 Fondazione IRCCS Policlinico San Matteo
 Pavia, Italy
Fondazione IRCCS Policlinico San Matteo
Pad. Nuovo Ospedale "DEA"
Piano +7 - Corpo A
Secretary + 39 382 502780
For Private Outpatient Appointment
Policlinico San Matteo: you can book an appointment by calling +39 382 501788 or by filling out the online form.
- Poliambulatorio Akesis viale Libertà 4, Pavia 
+39 382 302996


Examples of surgical treatment


Schwannoma of the VIIIth nerve on the right
54-year-old patient, in perfect health, almost total hearing loss on the right side.
The patient underwent tumor removal using a retrosigmoid approach (craniotomy of no more than 2 cm behind the ear). The tumor was completely removed and the facial nerve, after a period of approximately 8 months of malfunction, began to function perfectly again (on the right is the postoperative MRI image documenting the total removal).

Schwannoma of the VIIIth nerve on the left
A 39-year-old patient with a small schwannoma of the left vestibular nerve (1 cm) (left image). Deafness in the left ear. After discussing all possible treatments, the patient opted for surgical removal.
A translabyrinthine approach was performed with complete tumor removal. No facial nerve damage was observed (right image).


Neurinomas or schwannomas are benign tumors that arise from the sheath that surrounds nerves.
The most common ones at the central nervous system level are those that originate from the vestibular nerve, that is, the nerve transmits the impulses from the inner ear that allow us to stay balanced and move with ease.
This nerve is closely associated with the acoustic nerve (the nerve of hearing or cranial nerve VIII) and the facial nerve (cranial nerve VII), the nerve that allows us to smile and wink. All three form a thin string (the acoustic/facial bundle) that connects the ear to the brain. Therefore, a vestibular neuroma will always affect the other two nerves as well.
The most frequent symptoms that a patient may experience are:
hearing loss
dizziness
tinnitus
Obviously, when a neurinoma reaches considerable dimensions (>3 cm), other symptoms may also appear due to the contact of the tumor with areas surrounding the acoustic/vestibular/facial nerve.
difficulty swallowing
double vision (diplopia)
difficulty walking in a straight line
facial pain
severe headache
How is it treated?
Modern treatment of this disease requires a completely patient-specific approach. This means that each individual case presents unique characteristics, and therefore the therapeutic indications will vary.
The most important parameters that are taken into consideration in the therapeutic choice are
the dimensions
the symptoms
the position in relation to the brainstem and internal auditory canal
the age
the state of hearing ability
the presence of associated pathologies
Broadly speaking, there are three types of choices that can be made
1. observation (especially indicated in small tumors <1cm)
2. surgery (example of retrosigmoid approach)
3. radiosurgery
These strategies each have advantages and disadvantages which, once again, must be contextualized to the specific case.
Certainly, the patient must be able to understand all the therapeutic options in order to be best guided in his choice.
In our hospital, there is close collaboration between the neurosurgeon, ENT specialist, and radiotherapist/radiosurgeon, and all therapeutic options are offered and explained to the patient.
VESTIBULAR NEURINOMAS
In-depth analysis
Intraoperative electrophysiological monitoring
This technique requires the presence in the operating room of a Neurophysiologist, i.e. a doctor who is an expert in monitoring
electrophysiology of nerves and brain.
Monitoring allows for highly precise and safe real-time information on the functional status of a nerve. The principle is based on the application of a series of receiving electrodes (microscopic needles inserted into the muscles corresponding to the nerve being monitored, such as the facial muscles) and the application of very low-voltage currents to the nerve being examined. This provides information not only on the extent to which the nerve is being manipulated and irritated, but also on its functional integrity.
Surgery for tumors of the posterior cranial fossa and posterior skull base requires these monitoring procedures.
Our hospital offers a dedicated and highly experienced team of intraoperative electrophysiological monitoring specialists.